Involuntary shaking has many causes, but the most obvious one is a lack of coordination. This is why it’s common to see people shaking their heads vigorously to stay awake when they can’t sleep. Shaking can also happen when your muscles are overused – for example, when you’re trying to play a sport or play an instrument – and again, this is because your muscles aren’t coordinated. There are also a few drugs that can cause involuntary shaking, such as some anti-depressants and anti-epileptic drugs.
A recent study found that cannabis may reduce the severity of involuntary shaking in patients with Parkinson’s disease. Researchers found that patients using cannabis reported fewer problems with shaking compared to those not using the drug. The finding may have significant implications for patients, since involuntary shaking is a major symptom of the disease.
Scientists have been studying the effects of cannabis on involuntary movement for years. By studying rats that were given a drug that blocks neurotransmitters in the brain, they discovered that the rats were significantly less likely to shake uncontrollably. This improved mobility was found to correlate with lower levels of the neurotransmitter, dopamine, which is responsible for relaying messages between the brain and limbs.
In a controlled study on mice, scientists found that a certain synthetic cannabis reduces essential tremors – a potentially groundbreaking discovery for a condition that affects 10 million people in the United States alone. Researchers at the University of Copenhagen, Denmark, conducted the study and published their findings in the journal Nature Neuroscience. Essential tremor is a neurological disorder that causes involuntary, rhythmic shaking. Although this condition can affect any part of the body, it usually occurs in the hands and is most noticeable when a person is trying to perform simple actions, for example. For example, drinking from a glass or tying a shoelace. Although the condition is not dangerous in itself, it worsens over time and can make daily life extremely difficult for some people. Essential tremor is a different condition than Parkinson’s disease, which also causes tremor. The disease usually first appears in people over the age of 40. We focused on the essential tremor. It causes involuntary tremors that can be very distressing and severely limit the patient’s quality of life, said associate professor Jean-Francois Perrier, who led the research project, in a press release. However, the cannabinoid may also have positive effects, for example in the case of sclerosis and spinal cord injuries, which also cause involuntary tremors.
Cannabis activates an important group of cells called astrocytes.
The key to the study is its focus on astrocytes, which are cells in the spinal cord and brain. In this study, scientists showed that cannabis has the ability to activate these cells. This is important because astrocytes in the spinal cord and brain secrete a substance called adenosine, which reduces nerve activity. This reduction in nerve activity is the cause of the reduction in trembling in mice. The researchers used a particular type of synthetic cannabinoid called WIN55,212-2, which they injected directly into the spinal cord. The Danish researchers focused on the spinal cord because the activation of spinal neurons leads to both voluntary and involuntary movements. The tremor that occurs in essential tremor occurs when motor neurons simultaneously send out conflicting signals. Cannabis significantly reduced this activity.
What does this mean for people with essential tremor?
The approach by researchers at the University of Copenhagen marks a new direction in the use of cannabis. Previous studies have not focused on astrocytes. The next step for the researchers is to conduct a clinical trial in patients with essential tremor. Postdoctoral researcher Eva Maria Mayer Karlsen, of the neurology division of the university’s department of medical and health sciences, said in a press release that a new medicinal cannabis approach to treating tremors could be considered if – in developing cannabis-based drugs – treatments target the spinal cord or astrocytes – or, at best, astrocytes in the spinal cord. Carlsen also pointed out that the treatment does not affect the neurons in the brain responsible for memory and cognitive abilities, meaning patients can be treated for essential tremor without painful side effects.Some people have involuntary muscle movements, and they are very uncomfortable and are an indication that something is off. If you are one of these people, you can read this article to learn how cannabis can help you and stop that involuntary shaking.. Read more about best strain for tremors and let us know what you think.
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